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Gut microbiota derived indole-3-acetic acid ameliorates precancerous inflammatory intestinal milieu to inhibit tumorigenesis through IL-35

Ann Thorac Surg 83(5):1805-13

10.1523/JNEUROSCI.2329-14.2014 130 LiL.YangX

Patient data showed reduced expression of these pathways in B cells and T cells.[ref] This study points to the individuality of underlying genetic dysfunction that can affect multiple pathways, resulting in the symptoms of ME/CFS