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10.1016/j.jbc.2022.102654 18 HausladenA.QianZ.ZhangR.PremontR

Preclinical studies have demonstrated that FMT benefits DKD models by restoring gut microbiota composition, enhancing microbial diversity, and reducing tubulointerstitial injury and inflammatory cytokines [209]

These defects were also present in younger age groups, where they do not normally occur

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These findings indicate that MSG may trigger oxidative stress by suppressing the expression and activity of thioredoxin reductase, an important antioxidant enzyme in the liver