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Unc5B is known to bind Netrin-1 and other ligands via its extracellular domain and its deletion in mice leads to leakage of BBB and reduced Wnt/-catenin signalling

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(ii) Cuprizone-demyelination (CPZ-DE) group: Mice were provided with a diet containing 0.2% w/w CPZ blended with normal rodent chow for 5 weeks to induce consistent demyelination in many brain regions (Goldberg et al

KongQDaiLWangYZhangXLiCJiangSet alHSPA12B Attenuated acute myocardial ischemia/reperfusion injury via maintaining endothelial integrity in a PI3K/akt/mTOR-dependent mechanism

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Catechins donate an electron from a phenolic hydroxyl group and to scavenge free radicals and thus exhibit direct antioxidant properties [212,213,214]