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Lancet 403 , 16491659 (2024)

Prostaglandin E2 is a critical regulator of inflammation, inhibited NETosis by activation of the cAMPPKA pathway through the activation of its Gscoupled receptors, EP2 and EP4 [147]

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In a post-traumatic epilepsy rat model, an increase in PTGS2 protein and mRNA levels was noted after induction of seizures

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In order to determine whether the GMP-induced inhibition of GATA4 multimerization affected the recruitment of GATA4 by p300 to the promoter region of the target genes of GATA4, we performed a chromatin immunoprecipitation (ChIP) assay and an in vitro DNA pull-down assay