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A striking example is curcumins synergy with antibiotics against resistant organisms: curcumin greatly improved the efficacy of polymyxin and vancomycin against both Gram-negative and Gram-positive pathogens by increasing cell membrane permeability and blocking drug efflux ( Candida (fungal) cells as wellcurcumin interacts with membrane ergosterol, akin to polyene antifungals, leading to membrane destabilization

Effects of azithromycin on clinical isolates of Pseudomonas aeruginosa from cystic fibrosis patients

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J Intern Med 231:567570 Moling O, Cairon E, Rimenti G, Rizza F, Prister R, Mian P (2006) Severe hepatotoxicity after therapeutic doses of acetaminophen

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