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Recently, it has been reported 66 that the yield of membrane proteins expression in mammalian cells can vary by up to 5 folds when fused with different GFP variants

Figure 3 Among them, PRIMA-1 and PRIMA-1Met (APR246, eprenetapopt) have emerged as the first structural reactivators of mutant p53 variants recovering its transcriptional activity by covalent binding cysteines within the core domain (65)

"COPD: help your patients breathe easier." RN (2008)71(1):21-6

"N-acetylcysteine for antioxidant therapy: pharmacology and clinical utility." Expert Opin Biol Ther

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In addition, the fibroblast activation protein (FAP) inhibitor BR103354 blocks FGF-21 degradation, significantly prolonging half-life of FGF-21 and improving metabolic phenotypes and hepatic steatosis in diabetic mice [292]