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Massaging the injection site gently also increases blood flow and mitigates inflammation, further helping pain alleviation

10.1155/2017/2984826 173 ZhuX.-J.LinY.-J.ChenW.WangY.-H.QiuL.-Q.CaiC.-X.et al (2016)

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Furthermore, excessive accumulation of NADH in conjunction with reduced NAD + availability can inhibit glyceraldehyde-3-phosphate dehydrogenase (GAPDH) activity in the glycolytic pathway, leading to glucose shunting to the glycolytic branch pathway (Yan et al., 2016