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Together these observations are consistent with an important concept: microglia are the earliest responders to a primary multifocal myelin injury in the MS white matter, and importantly, this injury/response seems to precede lymphocytic infiltration, arguing against adaptive immune cells being the primary drivers of white matter injury

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Conceivably, this process is energy consumption that involves extensive metabolism

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CN0001/2013), FDA Establishment Registration (3013682254), and WHO PQ approval for veterinary parenteral products

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