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Topical fading agents, such as hydroquinone, may improve pigmentation where the excess melanin is confined to the epidermis but are of no use for pigment lying below the epithelium in dermal melanophages

Median follow-up was 8 months, and all patients had a minimum of 6 months of follow-up

Alcohol interaction: Unlike flibanserin (a womens HSDD drug that has a major alcohol contraindication), bremelanotide does not have a meaningful interaction with alcohol

Exposure to the sun or tanning lamps increases the risk of all types of skin cancer

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20 These cancers typically occur over the age of 50 years and males may be more commonly affected