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lycopersicum (Pusa sheetal cv.) has not yet been studied so far

doi: 10.1128/CMR.12.4.564 20 CramerC

PMID: 35710796 Exp Mol Med Simultaneous treatment with sorafenib and glucose restriction inhibits hepatocellular carcinoma in vitro and in vivo by impairing SIAH1-mediated mitophagy

524,525 In the liver, insulin suppresses the gluconeogenic enzymes PEPCK and G6 Pase via the Akt and FOXO pathways, 526,527 but resistance impairs this process, increasing glucose output

This study was retained in the DCD analysis due to its rigorous methodology, with its larger sample size (227 participants) and extended 12-month follow-up period likely contributing to the observed differences in effect size