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Its modus operandi closely mirrors that of ghrelin, a native hormone governing appetite and energy expenditure

Moreover, because MERCs formation serves as an important platform for MITOL-mediated ubiquitination of HMOX2, the effect of MERCs formation on mitochondrial iron homeostasis was assessed by measuring mitochondrial iron levels in PDZD8 KO and VAPB KO cells (Extended Data Fig

The list of clinical trials now includes around 2700 PD clinical studies as of this writing

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10.1021/np0603424 357 YaoJ

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