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There are theoretically hundreds of thousands of these peptides, Cohen says

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Over the past 10 years, the incidence of this malformation has been 56 per 10,000 live births

154,155 PTEN is an ASD risk gene located on chromosome 10q23 that encodes a lipid specific for phosphatidylinositol (3,4,5)-triphosphate (PIP3), which is a negative regulator of PI3K/AKT/mTORC1 signalling upstream of TSC1/TSC2, resulting in symptoms of ASD

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