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Studies concluded that a personalized combination of interventions in patients with PD could maximize the outcome, but only in some instances, such as (1) persistent symptoms and fluctuation, (2) progression of the disease and reemergence of the motor and non-motor symptoms, (3) severe side effects from the initial therapy, (4) deterioration of patient symptoms, and (5) drug-resistant dysphagia [106]

B12 injections deliver vitamin B12 directly into the body, making them a convenient option for patients who want energy and wellness support without relying only on oral supplements