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Based on mechanisms of action, they can be pooled into two groups: covalent and non-covalent inhibitors (Table 2)

Vitamin B12, or cobalamin, is a water-soluble vitamin derived from animal-based sources like red meat, dairy, and eggs

For individuals following a vegan or vegetarian diet , sublingual B12 provides an accessible way to prevent deficiency, as plant-based foods contain negligible amounts of bioavailable B12

Vitamin B6 helps the pancreas produce enzymes that aid indigestion

Such observations indicate that NNMT plays a beneficial role in regulating gluconeogenesis in hepatocytes

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