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Oral administration of JHU083 could penetrate brain tissue and significantly improve the survival rate of various MYC-driven medulloblastoma mouse models (Hanaford et al., 2019)

Our results demonstrated that metabolites accumulated in these disorders were responsible for inducing DNA damage, individually and in combination

Toxicology in Vitro 57:194202

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Hellstrom WJ, Kendirci M, Matern R et al: Single-blind, multicenter, placebo controlled, parallel study to assess the safety and efficacy of intralesional interferon alpha-2B for minimally invasive treatment for Peyronie's disease