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the Met + Pio group ( n = 75) received metformin plus pioglitazone (500 mg, 15 mg, respectively) and placebo (citric acid plus calcium carbonate), twice daily for 12 weeks

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Cushings disease is a relatively common but serious health condition caused by an overproduction of cortisol, a natural steroid in the body, from the adrenal glands

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Directions: For adults, take one (1) caplet four times daily, preferably with meals