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MAOB inhibitors bind to and inhibit MAOB, preventing dopamine degradation

doi: 10.3389/fcell.2024.1422746 29

Hcy self-oxidation generates ROS, disrupts redox homeostasis, and induces neuronal apoptosis via upregulation of Bax protein expression and activation of the caspase-3 pathway ( MMA further contributes to oxidative stress by impairing the mitochondrial respiratory chain complexes and energy metabolism