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Furthermore, the level of Nrf2 was increased, and the inflammatory indices NF-B, IL-1, IL-6, and TNF- were decreased in the treated group of mice

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While preclinical models have yielded valuable insights into microglial heterogeneity, many markers defined in rodent systems [e.g., arginase 1 (Arg1) or rodent-specific chitinase-like protein (Ym1)] have limited expression or different regulation in human microglia