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Pregnancy and breastfeeding are also contraindicated due to a lack of safety data for systemic use in these populations

As long as the in vitro studies translate to human physiology, these results further support the positive feedback loop between ROS concentration and viral load, resulting in a higher risk of severe infection in G6PD-deficient patients

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This result was further verified by the fluorescence staining of phosphorylation of P65 and P38, which showed that SP could inhibit the phosphorylation and translocation of P38 and P65 proteins in RANKL-induced BMMs (Fig

Moreover, EV were isolated from the cell culture medium (Fig