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This refined strategy represents a move from antioxidant therapy to redox-modulatory medicine, seeking to correct specific imbalances without disrupting essential redox communication networks

This is an autoimmune phenomenon, and the best examples are SLE, lymphoma, Hodgkins disease, and drugs (methyldopa)

Longer follow-up times primarily focused on pertinent clinical outcomes, including survival, are also vital, and research with treatment application is strongly advocated