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As mentioned earlier, it plays a crucial role in red blood cell production, DNA synthesis, and nerve cell maintenance

Indones J Clin Pathol Med Lab

Pfeifer, H., Conrad, M., Roethlein, D., Kyriakopoulos, A., Brielmeier, M., Bornkamm, G

Genomic amplification of PHGDH has also been linked to the transcriptional regulation of tumor suppressor genes and post-translational modifications via proteasomal degradation, thereby further promoting oncogenic pathways (57, 61)

These ocular delivery challenges impede the translation of ferroptosis-targeted therapies, emphasizing the urgency for novel targeted and sustained drug delivery systems

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