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With respect to dosage, the average reductions were: 2000 mcg: 71.5% (single data point) 1,000 mcg: 31.8% Although limited data are available for higher dosages, the findings support the efficacy of both oral and non-oral B12 formulations in modulating homocysteine levels

OSteen S, Comstock ML, Orozco JJ, Hamlin DK, Wilbur DS, Jones JC, et al

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This helps ensure controlled, clean finished material

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