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To further investigate these observations and confirm the cystine-dependent modulation of NRF2, we analyzed NRF2 expression in eight TNBC and five non-TNBC cell lines by Western blot

Moreover, preclinical investigations using ASD-like animal models reported that hyperserotonemia significantly reduced the motivation for social interest through inhibition of separation distress, potentially accounting for the social impairments found in ASD individuals (Ellenbroek et al., 2016

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