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Additionally, improving mitochondrial function, enhancing mitophagy, or preventing mitochondrial fragmentation could reduce mtDNA release and subsequent inflammatory signaling

Crohns disease pathobiont adherent-invasive E coli disrupts epithelial mitochondrial networks with implications for gut permeability

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Cremer J , Martin M , Redl H , et al

Furthermore, a high-protein diet markedly elevates the level of the phenylalanine derivative PAGln produced by the gut microbiota, exacerbating colitis symptoms in mouse models