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Key pharmacokinetic finding: In an 18-subject, single-dose, randomized crossover trial, a single oral dose of S-Acetyl Glutathione produced significantly higher rate (Cmax) and extent (AUCt) of plasma GSH absorption compared to an equivalent dose of standard oral L-Glutathione, with a median Tmax of 1.5 hours for both formulations

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This disruption ultimately leads to diminished bone formation and contributes to the development of osteoporosis [72, 73]

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