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Table IV [i] MASLD metabolic dysfunction-associated steatotic liver disease, TNF- tumor necrosis factor-, IL interleukin, CRP C-reactive protein, CCL2 C-C motif chemokine ligand 2, MCP-1 monocyte chemoattractant protein-1, CXCL10 C-X-C motif chemokine ligand 10, ICAM-1 intercellular adhesion molecule 1

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The advent of CRISPR , a gene-editing tool, has given researchers confidence that were on the verge of the gene-therapy era

Specifically, the gene ( Glyur000324s00015431 )-encoding HK, the gene ( Glyur000219s00011582 )-encoding PFK, the genes ( Glyur000136s00007955 and Glyur003994s00042985 )-encoding PDC, the gene ( Glyur000038s00004477 )-encoding ADH, the gene ( Glyur000698s00016570 )-encoding ALDH, the gene ( Glyur000278s00017282 )-encoding pdhB, and the gene ( Glyur000082s00007586 )-encoding pdhD were upregulated in S vs

Another important knowledge gap is how glutathione-S-transferase polymorphisms affect protein expression or activity of the glutathione-S-transferase enzymes or related proteins

This limitation hinders developing a unified dietary AGE/glycotoxin database