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Functional BBB permeability has also been evaluated by measuring the passage of fluorescent molecules of various sizes

Therapeutic peptides work on that same principle: you're not introducing a foreign substance (when manufactured safely), you're speaking the body's own language, just at a higher volume and for longer than it would naturally sustain

After washing, membranes were incubated with horseradish peroxidase-coupled secondary antibody (1:5000

This compensation does not influence the accuracy, neutrality, or integrity of the information presented

In this section, we will review the most used and promising tools for BBBP assessment and HT prediction, each of which has its own advantages and disadvantages (Table 1)

The choice directly influences project feasibility and publication horizon