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doi: 10.1039/c7mt00209b 110 ValderrabanoRJLinaresMI

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4 A decade of progress: novel antifungal drugs targeting resistance The main mechanism of antifungal action lies in inhibiting essential molecules, such as ergosterol (azole class) or 1,3--D-glucan (echinocandins), or by binding to ergosterol (polyene class), leading to the formation of pores and altering the integrity and permeability of the cell membrane, thereby affecting the membrane or fungal cell wall

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Author contributions NC: Writing original draft, Conceptualization, Data curation, Visualization

Ovarian steroids regulate gene expression in the dorsal raphe of old female macaques