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found that anti-PD-1, alone or in combination with anti-CTLA-4, failed to inhibit tumor growth in mice receiving a standard diet, whereas KD implementation, or oral administration of 3-hydroxybutyrate (3-HB), a principal KB generated in the KD, reestablished therapeutic responses

10.1038/ncomms8086 61 HuangQ.-Q.PerlmanH.HuangZ.BirkettR.KanL.AgrawalH.et al (2010)

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Growth hormone is considered to be a conducive hormone that enhances mitochondrial biogenesis

PL: -Poly-L-lysine

[The Working Group noted that, for all five studies, only one diet assessment was available at baseline, which was during a period that was relevant for aspartame exposure from ASBs, and the mean follow-up ranged from 11 to 16 years