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In case of SARS-CoV2, conceptually, Broad spectrum antiviral agents (BSAA) are more advantageous as repurposing agents as they targets two or more viral families

(2014): Antioxidant vitamins and magnesium and the risk of hearing loss in the US general population

PGC-1-related coactivator (PRC), a sensor of metabolic stress, orchestrates a redox-sensitive program of inflammatory gene expression

Zuo et al [15] found that patients with paroxysmal and persistent AF have distinct gut microbiota and metabolite profiles compared to non-AF individuals[15]

Sepsis, severe burns, and postoperative critical illness differ substantially in metabolic stress, muscle loss, and vulnerability of organ dysfunction, and future trials should therefore compare standard versus higher protein intakes and early versus delayed initiation strategies across distinct phases of illness, with endpoints including mortality, organ function, skeletal muscle outcomes, and functional recovery (5255, 67, 92, 94, 95, 127)

Deficiency also can lead to neurological changes such as numbness and tingling in the hands and feet [7,13]