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It has been reported that CKI can improve the clinical efficacy and reduce the side effects of conventional therapy

doi: 10.1128/AAC.47.5.1665-1671.2003, 16 FosterJ.GanatraM.KamalI.WareJ.MakarovaK

Hinshaw, Nico Tjandra Source : This study investigates the fibrillization of Humanin (HN) and its variants using transmission electron microscopy and other biophysical techniques

However, more research is needed to fully elucidate the mechanisms of action of MOTS-c and to translate these findings into therapeutic applications

But the unique physicochemical properties of nanoparticles like the ultra-small size, and high surface area, along with variable surface charge is understood to pose many safety concerns (Mellor and Uchegbu, 2022)