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The release and excessive accumulation of collagen fibers caused by overactivated fibroblasts, which are marked with fibroblast activation protein (FAP), lead to pathological changes in the extracellular matrix (ECM) and persistent inflammation, resulting in a vicious cycle of cellular activity and extracellular fibrosis 3,4,5,6,7

B12) to a cocktail of supplements (i.e

While moderate ROS levels can act as signaling molecules, influencing neuronal plasticity and synaptic function, excessive ROS production must be carefully controlled to prevent oxidative stress and cellular damage (Tommasini et al., 2024)

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