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The strongest phenotype of mitochondrial fragmentation was observed for monomeric, non-acetylated and deSUMOylase-active SnCE1 Y212A

PMID: 271 RuliatyL.PrayitnoS

4ab) concurrently induces DNA damage via the Pt(IV) moiety and suppresses DNA repair pathways through the PROTAC component, resulting in potent synergistic anticancer effects and improved membrane permeability, offering a viable strategy to circumvent platinum resistance

Isothiocyanates (ITCs) are bioactive substances found in cruciferous vegetables such as broccoli, cauliflower, watercress, and mustard

Two hypotheses may be applied to explain the apparent discrepancy observed in relation to our study

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