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NF-B increases the levels of the microRNA miR-34a, which inhibits nicotinamide adenine dinucleotide (NAD) synthesis by binding to its promoter region, [92] resulting in lower levels of sirtuin 1

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This evidence emerged from studies utilizing positron emission tomography (PET) to evaluate the levels of the 18-kDa translocator protein (TSPO) expressed by activated microglia [202]

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