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Indeed, one U.S.-based cohort study with a median 12.5 year follow-up isolated a specific, significant mediatory effect of TMAO-related metabolites on red meat-associated development of atherosclerotic CVD (ASCVD) [69]

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Doctors also prescribe it to patients undergoing dialysis, to replace levocarnitine which has been removed from the body as a result of this type of treatment

Epidemiological studies of the case-control and cohort design that have demonstrated an association between use of psychotropic drugs that interfere with serotonin reuptake and the occurrence of upper gastrointestinal bleeding have also shown that concurrent use of an NSAID or aspirin may potentiate the risk of bleeding

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