Okwundu et al., 2021
By exploring zincs influence on each component of the immune system, from innate responses mediated by neutrophils and macrophages to adaptive immunity regulated by T and B lymphocytes, this review underlines the importance of zinc for immune health in aging populations
IL-37 has been suggested for this purpose
Figure 3 5 Vitamin D in specific kidney diseases: mechanisms and clinical implications 5.1 Acute kidney injury Acute kidney injury (AKI) is a rapidly developing clinical syndrome with poor outcomes, which affects approximately 20% of hospitalized patients ( Epidemiological studies have shown that low serum 25(OH)D levels significantly increase the risk of AKI and dialysis demand ( Mechanistically, vitamin D exerts anti-inflammatory effects via VDR-mediated suppression of TLR signaling, induction of Treg expansion, and downregulation of proinflammatory cytokines such as TNF- and IL-6
Pretreatment with IL-1 and TNF- increased the frequency of spontaneous excitatory postsynaptic currents (sEPSCs) in lamina II neurons of isolated spinal cord preparations
HUBERMAN: Then we'll discuss therapeutic peptides specifically for longevity, both staving off tumor growth, as well as potentially, and I want to highlight potentially, increasing lifespan
