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TP0473292 is an adamantane carboxylic acid ester prodrug, which can be used as a novel antidepressant that enhances metabotropic glutamate 2/3 receptor antagonist oral bioavailability

Compound 102 passed the PAINS (pan assay interference compounds) remover, which filters out compounds that appear as frequent hitters (promiscuous compounds) in many biochemical high throughput screens

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Li Y, Yang W, Tang Y, Du S, Ye Y, Xu B, et al

In the study conducted by Kosza et al

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