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First, although SLC30A10 mediates the release of Mn from the brain and SLC39A8 facilitates its uptake 312 , the precise mechanisms that regulate neuronal Mn transport and accumulation remain poorly understood

doi: 10.3892/etm.2025.12821 [DOI] [PMC free article] [PubMed] [Google Scholar] 145.Zhang W, Ren H, Chen W, et al

Cells 38 (4), 327335

This led to GSH depletion, a burst of lipid peroxides, and accumulation of labile iron, collectively triggering ferroptosis

(iv) rapid protection vs

FIGURE 8 4 Conclusion In summary, a novel RBC-coated biomimetic self-cascade bioreactor (RBC@SeMSN@Uri) was designed and synthesized for the treatment of hyperuricemia and gout