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In addition, severe IMDD is associated with a reduction in the levels of natural immunoregulatory substances, including Clara cell protein (CC16), which function as inhibitors of IRS activation [32]

Clinical mechanisms include: Tyrosinase enzyme inhibition reducing active melanin synthesis Free radical neutralisation reducing oxidative triggers for pigmentation Glutathione peroxidase support protecting cellular membranes from oxidative degradation Hepatic detoxification enhancement supporting liver clearance of toxins that contribute to dull, uneven skin Anti-inflammatory action reducing chronic low-grade dermal inflammation that worsens pigmentation Collagen precursor support indirectly supporting skin firmness and elasticity through reduced oxidative collagen degradation IV Glutathione Treatment Protocol at Our Mumbai Clinic The specific IV formulation administered to each patient at our Andheri West clinic is determined following a pre-treatment medical consultation

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