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Using a clean and stable environment for administration

Medications: antibiotics and certain inflammation reducers, like nonsteroidal anti-inflammatory drugs (NSAIDs) Medical treatments: radiation therapy or blood transfusions Physical stimuli: exercise, tight clothing, or exposure to heat, cold, or sunlight Viral infections: mononucleosis, COVID19, and hepatitis Bacterial infections: strep throat and urinary tract infections Allergic reactions to latex, nickel, insect bites or stings, and certain foods can also produce acute hives

Zhu L, He S, Huang L, Ren D, Nie T, Tao K, et al

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Author contributions All authors listed have made a substantial, direct, and intellectual contribution to the work, and approved it for publication

Reduced RONS levels may also be attributable to the redox enzymes present in the VACV lateral bodies, which are released when the virus enters the cell