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Studies have demonstrated that DNA demethylation and histone (de)acetylation can trigger or increase Nrf2 expression

The MDR family includes two genes in man ( MDR1 and MDR2 ) and three in rodents ( mdr1 , 2 , 3 )

Ecotoxicol Environ Saf, 228 112918 10.1016/j.ecoenv.2021.112918 86

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A recent study demonstrated that SCFA supplementation in GF TE4 mice mitigated the neuroprotective effects of GF rearing, resulting in increased gliosis and tau pathology

While the initial exploration of GLO I inhibitors was rooted in anticancer drug development, there is emerging interest in their application in metabolic diseases [143]