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Pharmacol Res 175:106033 Yang B et al (2024) Circ DENND4C inhibits pyroptosis and alleviates ischemia-reperfusion acute kidney injury by exosomes secreted from human urine-derived stem cells

A small fraction of APAP is converted by CYP2E1 into the highly reactive NAPQI, which is normally detoxified by GSH

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doi: 10.1016/j.jcjd.2017.10.003 59 ZieglerDLandgrafRLobmannRReinersKRettKSchnellOet al

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It also inhibits Dusp2, reducing MAPK signaling and inflammation in collagen-induced arthritis