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Hypoxic-preconditioned mesenchymal stem cell-derived small extracellular vesicles inhibit neuronal death after spinal cord injury by regulating the SIRT1/Nrf2/HO-1 pathway

Eotaxin (CCL11) induces in vivo angiogenic responses by human CCR3+ endothelial cells

They are FDA-approved for medical use and have minimal side effects when taken under professional supervision

They dont have major side effects

Evacetrapib modestly reduced LDL-C, but its cardiovascular outcome trial was stopped early for futility due to limited statistical power [9]

These results propose that the impacts of MSCs are context and cell-type-dependent