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Residue 2 is glutamic acid, not proline

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In addition, IL-1 promotes fibrogenesis not only through c-Jun, TGF-, PI3K/Akt and ERK1/2 but also by promoting the expression of platelet-derived growth factor receptor (43), which then binds to platelet-derived growth factor to stimulate fibrosis

Thereinto, the antioxidant effect of CoQ10 may be partially attributed to activating the GSH system

Vermeulen L, De Sousa EMF, van der Heijden M, Cameron K, de Jong JH, Borovski T, et al