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The -catenin translocation is inhibited by the natural chemical fucoidan, which significantly suppresses the Smad2 and ERK1/2 signaling pathways [159]

Ye et al., 2020

Furthermore, access to alternative steroid-sparing agents such as ISs and biologics remains limited due to high costs and restricted healthcare infrastructure, leading to a cycle of repeated steroid use [32]

Curr Opin Plant Biol

It is rich in a bioactive compound that can effectively help in fading and reducing dark spots and other signs of pigmentation (6), (7)

Benton CB, Boddu PC, DiNardo C, Bose P, Wang F, Pemmaraju N, Devendra KC, Pierce S, Patel K, Konopleva M, Ravandi F, Garcia-Manero G, Kadia T, Cortes J, Kantarjian H, Andreeff M , and Verstovsek S