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and quantified using a radioisotope scanner

High glucose-induced endothelial STING activation inhibits diabetic wound healing through impairment of angiogenesis

To be beneficial, the inflammatory reaction must be acute, destroying an injurious agent within a short period of time and in a localized area, while inducing an immune response

However, when it was tested in humans, it worsened stroke outcome and was associated with ICH, cardiac arrest, and meningitis [113,129]

[DOI] [PubMed] [Google Scholar] 105.Shelar S.B., Narasimhan M., Shanmugam G., Litovsky S.H., Gounder S.S., Karan G., Arulvasu C., Kensler T.W., Hoidal J.R., Darley-Usmar V.M., et al

Cells generate localized ROS near the nuclear envelope (NOX isoforms), the outer mitochondrial membrane (MAO facing the cytosol) and cytosolic dehydrogenase complexes adjoining the nucleus (Kaludercic et al