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(Piazzolla et al., 2019) conducted a cross-sectional analysis of MetS patients, noting elevated Hcy levels in a considerable proportion of cases

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In the rat model, treatment with recombinant aPC improved neurological function, inhibited pyroptosis in a dose-dependent manner, and alleviated EBI caused by aSAH by suppressing NLRP3 inflammasome activation (105, 106)

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Research has shown that AGPS (alkyl-dihydroxyacetone phosphate synthase) and FAR1 (fatty acid reductase 1) are key enzymes in the biosynthesis of ePLs, and enhancing their expression can promote neuronal ferroptosis (Zou et al., 2020a)

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