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Association of the MTHFR C677T and A1298C polymorphisms with methotrexate toxicity in rheumatoid arthritis: a meta-analysis

Enhancing glycine/D-serine concentrations, therefore, is expected to potentiate NMDA signaling

Small-molecule agonists of TrkB (e.g., 7,8-dihydroxyflavone) can penetrate the blood-brain barrier and potentially activate BDNF signaling while supporting mitochondrial function [120], but their specificity and long-term safety in humans remain questionable, and they do not address the fundamental barrier of blood-brain barrier penetration for large-molecule NTFs (e.g., GDNF)

The International Reflux Study in Children

The apparatus and procedures used for all these tasks were exactly similar as described earlier 63 which is provided in detail in the supplementary file