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It contains structural changes that extend its half-life and reduce binding to IGF-binding proteins, allowing it to remain active in circulation longer than endogenous IGF-1

Zhao et al., 2015)

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5.2 Lifestyle modifications in CKD management 5.2.1 Dietary interventions Limiting the intake of sodium, protein, phosphorus, and potassium is generally recommended in patients with CKD, while foods rich in fiber, vitamins, and minerals are greatly advised (Yang et al., 2018

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Position the patients feet to avoid pressure on the heels when seated in a chair