interaction of chloroacetamide electrophiles with cellular glutathion Transduction Redox Signaling by Electrophile-Protein Reactions Accelerating multiplexed profiling of protein-ligand
Accelerating multiplexed profiling of protein ligand interactions: High throughput plate based reactive cysteine profiling with minimal input ScienceDirect Electrophilic compound screening identifies GPX4 dependent ferroptosis as a senescence vulnerability Nature Cell Biology Sulfamate Acetamides as Self Immolative Electrophiles for Covalent Ligand Directed Release Chemistry Journal of the American Chemical Society Application of a MALDI mass spectrometry assay to identify covalent fragments targeting the methyl lysine reader protein MPP8 SLAS Discovery Development of a Highly Selective Ferroptosis Inducer Targeting GPX4 with 2 Ethynylthiazole 4 carboxamide as Electrophilic Warhead Journal of Medicinal Chemistry Selective covalent targeting of GPX4 using masked nitrile oxide electrophiles Nature Chemical Biology
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